广州市统计五年的结果发现,冠状病毒阳性者,有1/3感染其他病毒,主要是流感。
跟美国情况类似。
Of the 294 HCoV positive patients, 34.69% (101 cases) were co-infected by
other common respiratory viruses, and influenza virus was the most common co
-infecting virus (30/101, 29.70%).
美国Ohio州研究结果:Of 832 adult respiratory specimens screened, 13 (1.6%) cases of CoV-HKU1 were identified. Adults age ranged between 23 and 75 years and 6 (46%) were males. All of whom had 1 or more respiratory symptoms, and 5 (38%) also reported 1 or more gastrointestinal symptoms. Eleven (85%) reported history of smoking and 5 (38%) used inhaled steroids. Seven (54%) required hospitalization, 5 (71%) of these needed supplemental oxygen, and 2 (29%) were admitted to intensive care. Median length of hospitalization was 5 days. Eight (62%) received antibiotics despite identification of CoV-HKU1. Infectious work-up in 1 patient who died did not reveal any other pathogen. In 2 (15%) CoV-HKU1-positive adults, the only viral coinfection detected was influenza A. 15%冠状病毒感染者同时感染A型流感。
这些双重感染者更容易发展成重症,注射流感疫苗后,同时感染流感病毒的可能性大大降低,减少重症患者,降低死亡率。